We are looking for a student with very good Matlab programming skills, and good knowledge of data analysis and statistics approaches to help with the analyses of very large in vivo calcium imaging datasets.
Developing a setup for behavioral training in mice. The ambitious goal is to build up new hardware and software and a state-of-the-art setup. Once the setup is ready, this project includes animal handling and training, and the analysis of data.
In this electrophysiological project we will use patch clamp, intracellular electrodes and multielectrode arrays to record responses of retinal neurons and use information theory and linear/non-linear system analysis to determine how and with what efficiency visual information is coded in the outer retina.
For this project the fish are tested in behavioral tasks using optokinetic, startle and optomotor assays. Furthermore, the electrical responses of the eye are evaluated using ERG measurements and the morphology of the retina is studied using morphological techniques.
The group is driven by the general question: “How do we control our behavior?”, and is specifically interested in “compulsivity” and the effects of “deep-brain stimulation” on compulsive behavior. The student will be involved in one of the projects that are available.