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Publicaties

La Fleur Groep

S R Ruigrok, J M Kotah, J E Kuindersma, E Speijer, A A S van Irsen, S E la Fleur, A Korosi Adult food choices depend on sex and exposure to early-life stress Neurobiology of stress 15 (2021) 100360 Download

La Fleur Groep

Müzeyyen Ugur, Stéphane Doridot, Susanne E la Fleur, Pierre Veinante, Dominique Massotte Connections of the mouse subfornical region of the lateral hypothalamus (LHsf) Brain Structure & Function 226 (2021) 2431-2458 Download

La Fleur Groep

Laura L Koekkoek, Margo Slomp, Julien Castel, Michael Mutersbaugh, Ian Linville, Mireille J Serlie, Serge H Luquet, Susanne E la Fleur Disruption of lateral hypothalamic calorie detection by a free choice high fat diet FASEB Journal 35 (2021) e21804 Download

Kalsbeek Groep, La Fleur Groep

Anil Joshi, Tess Kool, Charlene Diepenbroek, Laura L Koekkoek, Leslie Eggels, Andries Kalsbeek, Joram D Mul, Michel Barrot, Susanne E la Fleur Dopamine D1 receptor signalling in the lateral shell of the nucleus accumbens controls dietary fat intake in male rats Appetite 167 (2021) 105597 Download

La Fleur Groep

Myrtille C R Gumbs, Leslie Eggels, Anna H Vuuregge, Unga A Unmehopa, Joram D Mul, Susanne E la Fleur Effects of Neuropeptide Y administration into the lateral hypothalamus on intake of free-choice high-fat high-sucrose diet components of the male Wistar rat Nutritional Neuroscience (2021) Download

La Fleur Groep

Clarissa M Maya-Monteiro, Felipe Corrêa-da-Silva, Susanna S Hofmann, Matthijs K C Hesselink, Susanne E la Fleur, Chun-Xia Yi Lipid Droplets accumulate in the hypothalamus of mice and humans with and without metabolic diseases Neuroendocrinology 111 (2021) 263-272 Download

La Fleur Groep

Stan R Ursem, Charlene Diepenbroek, Vesna Bacic, Unga A Unmehopa, Leslie Eggels, Clarissa M Maya-Monteiro, Annemieke C Heijboer, Susanne E la Fleur Localization of Fibroblast Growth Factor 23 protein in the Rat Hypothalamus The European journal of neuroscience 54 (2021) 5261-5271 Download

La Fleur Groep

Anil Joshi, Fanny Faivre, Susanne Eva la Fleur, Michel Barrot Midbrain and lateral nucleus accumbens dopamine depletion affects free-choice high-fat high-sugar diet preference in male rats Neuroscience 467 (2021) 171-184 Download

Kalsbeek Groep, La Fleur Groep

L L Koekkoek, A Masís-Vargas, T Kool, L Eggels, L L van der Gun, K Lamuadni, M Slomp, C Diepenbroek, A Kalsbeek, S E la Fleur Sucrose drinking mimics effects of nucleus accumbens µ-opioid receptor stimulation on fat intake and brain c-Fos-expression Nutritional Neuroscience (2021) Download

La Fleur Groep

Katy A van Galen, Jan Booij, Anouk Schrantee, Sofie M Adriaanse, Unga A Unmehopa, Eric Fliers, Gary J Schwartz, Ralph J DiLeone, Kasper W Ter Horst, Susanne E la Fleur, Mireille J Serlie The response to prolonged fasting in hypothalamic serotonin transporter availability is blunted in obesity Metabolism: Clinical and Experimental 123 (2021) 154839 Download

La Fleur Groep, Kalsbeek Groep

Rianne Van Der Spek, Ewout Foppen, Eric Fliers, Susanne La Fleur, Andries Kalsbeek Thermal lesions of the SCN do not abolish all gene expression rhythms in rat white adipose tissue, NAMPT remains rhythmic Chronobiology International 38 (2021) 1354-1366 Download

La Fleur Groep

L L Koekkoek, U A Unmehopa, L Eggels, T Kool, K Lamuadni, C Diepenbroek, J D Mul, M J Serlie, S E la Fleur A free-choice high-fat diet modulates the effects of a sucrose bolus on the expression of genes involved in glucose handling in the hypothalamus and nucleus accumbens Physiology & Behavior 222 (2020) 112936 Download

La Fleur Groep

M C R Gumbs, L Eggels, T Kool, U A Unmehopa, J K van den Heuvel, K Lamuadni, J D Mul, S E la Fleur Neuropeptide Y Signaling in the Lateral Hypothalamus Modulates Diet Component Selection and is Dysregulated in a Model of Diet-Induced Obesity Neuroscience 447 (2020) 28-40 Download

La Fleur Groep, Kalsbeek Groep

Johanneke E Oosterman, Laura L Koekkoek, Ewout Foppen, Unga A Unmehopa, Leslie Eggels, Joanne Verheij, Eric Fliers, Susanne E la Fleur, Andries Kalsbeek Synergistic Effect of Feeding Time and Diet on Hepatic Steatosis and Gene Expression in Male Wistar Rats Obesity 28 (2020) S81-S92 Download

La Fleur Groep, Kalsbeek Groep, Swaab Groep, Huitinga Groep

Martin Jt Kalsbeek, Samantha Ec Wolff, Nikita L Korpel, Susanne E la Fleur, Johannes A Romijn, Eric Fliers, Andries Kalsbeek, Dick F Swaab, Inge Huitinga, Elly M Hol, Chun-Xia Yi The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia JCI insight 5 (2020) Download

La Fleur Groep

Myrtille C R Gumbs, Anna H Vuuregge, Leslie Eggels, Unga A Unmehopa, Khalid Lamuadni, Joram D Mul, Susanne E la Fleur Afferent Neuropeptide Y projections to the ventral tegmental area in normal-weight male Wistar rats Journal of Comparative Neurology 527 (2019) 2659-2674 Download

La Fleur Groep, Kalsbeek Groep

Dirk Jan Stenvers, Frank A J L Scheer, Patrick Schrauwen, Susanne E la Fleur, Andries Kalsbeek Circadian clocks and insulin resistance Nature Reviews Endocrinology 15 (2019) 75-89 Download

La Fleur Groep, Kalsbeek Groep

Irina V Milanova, Martin J T Kalsbeek, Xiao-Lan Wang, Nikita L Korpel, Dirk Jan Stenvers, Samantha E C Wolff, Paul de Goede, Annemieke C Heijboer, Eric Fliers, Susanne E la Fleur, Andries Kalsbeek, Chun-Xia Yi Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner Frontiers in Endocrinology 10 (2019) 424 Download

La Fleur Groep

M. Rijnsburger, U A Unmehopa, L. Eggels, Mireille J Serlie, S E la Fleur One-week exposure to a free-choice high-fat high-sugar diet does not disrupt blood-brain barrier permeability in fed or overnight fasted rats Nutritional Neuroscience 22 (2019) 541-550 Download

La Fleur Groep

Margo Slomp, Evita Belegri, Aurea S Blancas-Velazquez, Charlene Diepenbroek, Leslie Eggels, Myrtille C R Gumbs, Anil Joshi, Laura L Koekkoek, Khalid Lamuadni, Muzeyyen Ugur, Unga A Unmehopa, Susanne E la Fleur, Joram D Mul Stressing the importance of choice - validity of a preclinical free-choice high-caloric diet paradigm to model behavioral, physiological, and molecular adaptations during human diet-induced obesity and metabolic dysfunction Journal of Neuroendocrinology 31 (2019) e12718 Download

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