You will investigate cellular circuits in the cortex (or hippocampus) and perform functional characterizations of single neurons in combination with other techniques, such as immunofluorescence.
The Synapse and Network Development (SND) Lab has an outstanding opportunity for a PhD-student position or Post-doctoral researcher position for In vivo imaging and electrophysiology of developing cortical circuits
We are looking for a student with very good Matlab programming skills, and good knowledge of data analysis and statistics approaches to help with the analyses of very large in vivo calcium imaging datasets.
In this electrophysiological project we will use patch clamp, intracellular electrodes and multielectrode arrays to record responses of retinal neurons and use information theory and linear/non-linear system analysis to determine how and with what efficiency visual information is coded in the outer retina.
For this project the fish are tested in behavioral tasks using optokinetic, startle and optomotor assays. Furthermore, the electrical responses of the eye are evaluated using ERG measurements and the morphology of the retina is studied using morphological techniques.
The group studies the neurobiological basis of reinforcement learning, decision making, and compulsive behavior. We are driven by the question “How do we control our behavior?” and “How do we lose control?”.The student will be involved in one of the projects that are available.
Animal handling and training, programming, extracellular recordings and/or two-photon imaging, data analysis, possibly extended with histological techniques and microscopy.
We investigate neural mechanisms underlying visual information processing in humans. Research techniques include mainly psychophysics, eye-tracking and fMRI.
Onderzoek